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Antigenic Specificity | NUAK2 |
Clone | [378CT15.4.5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged NUAK2 protein(Fragment) was used to produced this monoclonal antibody. Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. |
Immunogen | n/a |
Other Names | [NUAK family SNF1-like kinase 2; Omphalocele kinase 2; SNF1/AMP kinase-related kinase; SNARK; NUAK2 {ECO:0000312|EMBL:AAH173061}; OMPHK2; SNARK] |
Gene, Accession # | [NUAK2], Gene ID: 81788, NCBI: NP_112214.1, UniProt: Q9H093 |
Catalog # | MBS9200039 |
Price | $165, $370 |
Order / More Info | NUAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Koh, H.J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15541-15546(2010) Rune, A., et al. Diabetologia 52(10):2182-2189(2009) Kuga, W., et al. Biochem. Biophys. Res. Commun. 377(4):1062-1066(2008) Kim, J.H., et al. Leuk. Lymphoma 49(7):1392-1398(2008) Yamamoto, H., et al. Biochem. Biophys. Res. Commun. 365(3):541-547(2008) |