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Antigenic Specificity | Alsin/ALS2 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alsin2 specifically binds to, and functions as a guanine nucleotide exchange factor (GEF) for the small GTPase RAB5. It contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. |
Immunogen | n/a |
Other Names | [Alsin; Alsin; alsin; alsin Rho guanine nucleotide exchange factor ALS2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein], [ALS2; ALS2; ALSJ; PLSJ; IAHSP; ALS2CR6; ALS2CR6; KIAA1563] |
Gene, Accession # | [ALS2], Gene ID: 57679, NCBI: Q96Q42.2, UniProt: Q96Q42 |
Catalog # | MBS555905 |
Price | $425 |
Order / More Info | Alsin/ALS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |