HM13 (C-term), 325-354 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HM13 (C-term), 325-354 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.43 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human HM13. The protein encoded by this gene, which localizes to theendoplasmic reticulum, catalyzes intramembrane proteolysis of somesignal peptides after they have been cleaved from a preprotein.This activity is required to generate signal sequence-derived humanlymphocyte antigen-E epitopes that are recognized by the immunesystem, and to process hepatitis C virus core protein. The encodedprotein is an integral membrane protein with sequence motifscharacteristic of the presenilin-type aspartic proteases. Multipletranscript variants encoding several different |
| Immunogen | n/a |
| Other Names | [Minor histocompatibility antigen H13; 3423-; Intramembrane protease 1; IMP-1; IMPAS-1; hIMP1; Presenilin-like protein 3; Signal peptide peptidase; HM13; H13; IMP1; PSL3; SPP] |
| Gene, Accession # | [HM13], Gene ID: 81502, NCBI: NP_110416.1, UniProt: Q8TCT9 |
| Catalog # | MBS9213739 |
| Price | $165, $370 |
| Order / More Info | HM13 (C-term), 325-354 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sato, T., et al. Biochemistry 45(28):8649-8656(2006) Loureiro, J., et al. Nature 441(7095):894-897(2006) Urny, J., et al. Biochim. Biophys. Acta 1759 (3-4), 159-165 (2006) : Friedmann, E., et al. J. Biol. Chem. 279(49):50790-50798(2004) Soares, M.R., et al. FEBS Lett. 560 (1-3), 134-140 (2004) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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