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Antigenic Specificity | PREX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3, 4, 5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Immunogen | Immunogen: Recombinant human Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592AA) |
Other Names | [Phosphatidylinositol 3; 4; 5-trisphosphate-dependent Rac exchanger 2 proteinP-Rex2PtdIns(3; 4; 5)-dependent Rac exchanger 2; DEP domain-containing protein 2; PREX2; DEPDC2] |
Gene, Accession # | [PREX2], Gene ID: 80243, NCBI: NP_079146.2, UniProt: Q70Z35 |
Catalog # | MBS7050465 |
Price | $160, $235 |
Order / More Info | PREX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |