Edit |   |
---|---|
Antigenic Specificity | TRPM7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
Immunogen | Immunogen: Recombinant human Transient receptor potential cation channel subfamily M member 7 protein (756-855AA) |
Other Names | [Transient receptor potential cation channel subfamily M member 7; Channel-kinase 1; Long transient receptor potential channel 7; LTrpC-7; LTrpC7; TRPM7; CHAK1; LTRPC7] |
Gene, Accession # | [TRPM7], Gene ID: 54822, NCBI: NP_001288141.1, UniProt: Q96QT4 |
Catalog # | MBS7046586 |
Price | $120, $160 |
Order / More Info | TRPM7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |