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Antigenic Specificity | IRF2BP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of IRF2BP2 are known to exist; this antibody will detect both. IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against an 17 amino acid peptide near the amino terminus of human IRF2BP2. |
Other Names | [Interferon regulatory factor 2 binding protein 2, IRF2 binding protein 2] |
Gene, Accession # | [IRF2BP2], Gene ID: 359948, NCBI: NP_892017 |
Catalog # | MBS9402294 |
Price | $320 |
Order / More Info | IRF2BP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |