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Antigenic Specificity | CREBBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CREBBP (NP 004371.2). |
Other Names | [CBP; RSTS; KAT3A; RSTS1] |
Gene, Accession # | [CREBBP], Gene ID: 1387, NCBI: NP_001073315.1, UniProt: Q92793 |
Catalog # | MBS8544365 |
Price | $280 |
Order / More Info | CREBBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |