MAVS (C-term), 477-505 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MAVS (C-term), 477-505 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAVS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MAVS. Double-stranded RNA viruses are recognized in a celltype-dependent manner by the transmembrane receptor TLR3 (MIM603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) andRIGI (ROBO3; MIM 608630). These interactions initiate signalingpathways that differ in their initial steps but converge in theactivation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB(IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1(MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM603734). Activated IRF3 and NFKB induce transcript |
| Immunogen | n/a |
| Other Names | [Mitochondrial antiviral-signaling protein; MAVS; CARD adapter inducing interferon beta; Cardif; Interferon beta promoter stimulator protein 1; IPS-1; Putative NF-kappa-B-activating protein 031N; Virus-induced-signaling adapter; VISA; MAVS; IPS1; KIAA1271; VISA] |
| Gene, Accession # | [MAVS], Gene ID: 57506, NCBI: NP_001193420.1, UniProt: Q7Z434 |
| Catalog # | MBS9213847 |
| Price | $165, $370 |
| Order / More Info | MAVS (C-term), 477-505 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sebastiani, P., et al. Science (2010) In press : Wang, X., et al. Cell. Mol. Immunol. 7(5):341-348(2010) Graef, K.M., et al. J. Virol. 84(17):8433-8445(2010) Wei, C., et al. J. Immunol. 185(2):1158-1168(2010) Onoguchi, K., et al. PLoS Pathog. 6 (7), E1001012 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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