FOXP3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-FOXP3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | FOXP3 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. FOXP3(forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcr |
| Immunogen | Immunogen: E Coli-derived human FOXP3 recombinant protein (Position: H101-P431). Human FOXP3 shares 88% amino acid (aa) sequence identity with mouse FOXP3. |
| Other Names | [Forkhead box protein P3; AIID; DIETER; Forkhead box P3; Forkhead box protein P3; foxp3; FOXP3_HUMAN; FOXP3delta7; Immune dysregulation polyendocrinopathy enteropathy X linked; Immunodeficiency polyendocrinopathy enteropathy X linked; IPEX; JM2; MGC141961; MGC141963; OTTHUMP00000025832; OTTHUMP00000025833; OTTHUMP00000226737; PIDX; SCURFIN; XPID; forkhead box P3], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX] |
| Gene, Accession # | [FOXP3], Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1 |
| Catalog # | MBS177894 |
| Price | $315 |
| Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Allan, S. E., Passerini, L., Bacchetta, R., Crellin, N., Dai, M., Orban, P. C., Ziegler, S. F., Roncarolo, M. G., Levings, M. K.The role of 2 FOXP3 isoforms in the generation of human CD4 Tregs.J. Clin. Invest. 115: 3276-3284, 2005. 2. Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M. E., Ferguson, P. J., Whitesell, L., Kelly, T. E., Saulsbury, F. T., Chance, P. F., Ochs, H. D.The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.Nature Genet. 27: 20-21, 2001. 3. Hong, J., Li, N., Zhang, X., Zheng, B., Zhang, J. Z.Induction of CD4 CD25 regulatory T cells by copolymer-I through activation of transcription factor Foxp3.Proc. Nat. Acad. Sci. 102: 6449-6454, 2005. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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