VE-Cadherin (Phospho-Tyr731) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVE-Cadherin (Phospho-Tyr731)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of VE-Cadherin only when phosphorylated at tyrosine 731. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. Wessel F, et al. (2014) Nat Immunol 15, 223-30 Sawada J, et al. (2012) Cancer Cell 22, 235-49 Turowski P, et al
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin.
Other Names[Vascular endothelial cadherin; VE-cadherin; 7B4 antigen; CDH5; CD144 antigen]
Gene, Accession #Gene ID: 1003, NCBI: NP_001786.2, UniProt: P33151
Catalog #MBS9411448
Price$200, $255
Order / More InfoVE-Cadherin (Phospho-Tyr731) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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