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Antigenic Specificity | VPS52 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology. Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061). |
Immunogen | Immunogen: Vacuolar protein sorting 52 homolog (S. cerevisiae) Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
Other Names | [ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52] |
Gene, Accession # | [VPS52], Gene ID: 6293, NCBI: NP_001276104.1 |
Catalog # | MBS7605680 |
Price | $290 |
Order / More Info | VPS52 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |