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Antigenic Specificity | BIP/GRP78 |
Clone | [3B4-H11-C9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as ' immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.The HSP70 proteins are ubiquitous molecular chaparones th |
Immunogen | Immunogen: Purified recombinant fragment of human HSPA5 expressed in E. Coli. |
Other Names | [BIP; MIF2; GRP78; FLJ26106; HSPA5; HSPA5] |
Gene, Accession # | [BIP/GRP78], Gene ID: 3309, NCBI: NP_005338.1, UniProt: P11021 |
Catalog # | MBS8538611 |
Price | $280 |
Order / More Info | BIP/GRP78 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |