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Antigenic Specificity | COX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC-P in Human, Rat. Background: Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene was approximately 40 kb long, with 11 protein-coding exons. There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the PTGS1 gene maps to chromosome 9. Human prostaglandin endoperoxide synthase exhibited 91% amino acid identity with the sheep enzyme. Prostaglandin synthase 1 gene disruption in mic |
Immunogen | Immunogen: E Coli-derived human COX1 recombinant protein (Position: E318-L599). Human COX1 shares 90% and 89% amino acid (aa) sequence identity with mouse and ratCOX1, respectively. |
Other Names | [Prostaglandin G/H synthase 1; prostaglandin-endoperoxide synthase 1; COX 1; COX 3; COX-1; COX1; COX3; Cyclooxygenase 1; Cyclooxygenase 3, included; Cyclooxygenase-1; Cyclooxygenase1; EC 1.14.99.1; Partial COX1 proteins, included; PCOX 1; PCOX1; PGG/HS; PGH synthase 1; PGH1_HUMAN; PGHS 1; PGHS-1; PGHS1; PHS 1; PHS1; Prostaglandin endoperoxide synthase 1; Prostaglandin G/H synthase 1; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H Synthase 1; Prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); Prostaglandin-endoperoxide synthase 1; PTGHS; PTGS 1; PTGS1], [PTGS1; PTGS1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1] |
Gene, Accession # | [PTGS1], Gene ID: 5742, NCBI: P23219.2, UniProt: P23219 |
Catalog # | MBS176993 |
Price | $315 |
Order / More Info | COX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |