Accn2 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Accn2 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against Accn2. It was validated on Western BlotTarget Description: Accn2 is a cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. It also permeable for Ca2+, Li+ and K+. It generates a biphasic current with a fast inactivating and a slow sustained phase and mediates glutamate-independent Ca2+ entry into neurons upon acidosis. This Ca2+ overloading is toxic for cortical neurons and may be in part responsible for ischemic brain injury. Heteromeric channel assembly seems to modulate channel properties. Accn2 functions as a postsynaptic proton receptor that influences intracellular Ca2+ concentration and calmodulin-dependent p |
| Immunogen | n/a |
| Other Names | [acid-sensing ion channel 1 isoform 1; Acid-sensing ion channel 1; acid-sensing ion channel 1; acid-sensing (proton-gated) ion channel 1; Acid-sensing ion channel; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2; BNaC2] |
| Gene, Accession # | [ASIC1], Gene ID: 11419, NCBI: NP_033727, UniProt: Q6NXK8 |
| Catalog # | MBS3202407 |
| Price | $335 |
| Order / More Info | Accn2 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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