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Antigenic Specificity | Integrin beta1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Integrin beta1 antibody detects endogenous levels of total Integrin beta1. Function: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors |
Immunogen | Immunogen: A synthesized peptide derived from human Integrin beta1 Subcellular Location: Cell Membrane, Sarcolemma. Cell Junction. In cardiac muscle, isoform 5 is found in costameres and intercalated disks and cell membrane. Cell Projection, Invadopodium Membrane. Cell Projection, Ruffle Membrane. Recycling Endosome. Melanosome. Cleavage Furrow. Cell Projection, Lamellipodium. Cell Projection, Ruffle. Cell Junction, Focal Adhesion. Cell Surface. Isoform 2 does not localize to focal adhesions. Hi |
Other Names | [beta1 integrin; CD29; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; GP IIa; GPIIA; Integrin beta-1; Integrin subunit beta 1; integrin VLA-4 beta subunit; Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITB1_HUMAN; ITGB1; MDF2; MSK12; OTTHUMP00000019420; Very late activation protein, beta polypeptide; VLA BETA; VLA-4 subunit beta; VLA-BETA; VLAB; VLAbeta] |
Gene, Accession # | [ITGB1], Gene ID: 3688, NCBI: NP_002202.2, UniProt: P05556 |
Catalog # | MBS9601551 |
Price | $240, $280 |
Order / More Info | Integrin beta1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sun L, Xu X, Chen Y, Zhou Y, Tan R, Qiu H, Jin L, Zhang W, Fan R, Hong W, Wang T; Journal: Oncogene. Rab34 regulates adhesion, migration, and invasion of breast cancer cells. |