CAS Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CAS |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CAS antibody detects endogenous levels of total CAS. Function: Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compar |
| Immunogen | Immunogen: A synthesized peptide derived from human CAS Subcellular Location: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Detected in brain, placenta, ovary, testis and trachea (at protein level) (PubMed:10331944). Widely expressed (PubMed:10331944). Highly expressed in testis and in proliferating cells (PubMed:7479798, PubMed:10331944). |
| Other Names | [CAS; Cellular apoptosis susceptibility protein; Chromosome segregation 1 (yeast homolog) like; Chromosome segregation 1 Like; Chromosome segregation 1 like protein; Chromosome segregation 1-like protein; Chromosome segregation gene CSE1; CSE 1; CSE 1 chromosome segregation 1 like; CSE 1 chromosome segregation 1 like protein; CSE 1L; CSE1; CSE1 chromosome segregation 1 like (yeast); CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1 like protein; CSE1L; Exp 2; Exp2; Exportin 2; Exportin-2; Exportin2; Importin alpha re exporter; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO 2; XPO2; XPO2_HUMAN] |
| Gene, Accession # | [CAS], Gene ID: 1434, NCBI: NP_001243064.1, UniProt: P55060 |
| Catalog # | MBS9602075 |
| Price | $240, $280 |
| Order / More Info | CAS Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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