PYDC1 (Center), 13-42 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PYDC1 (Center), 13-42 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PYDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the Central region of human PYDC1. PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. |
| Immunogen | n/a |
| Other Names | [Pyrin domain-containing protein 1; PAAD-only protein 1; Pyrin-only protein 1; PYDC1; ASC2; ASCI; POP1; PYC1] |
| Gene, Accession # | [PYDC1], Gene ID: 260434, NCBI: NP_690865.1, UniProt: Q8WXC3 |
| Catalog # | MBS9213649 |
| Price | $165, $370 |
| Order / More Info | PYDC1 (Center), 13-42 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Son, Y.L., et al. Biochem. J. 410(2):319-330(2008) Natarajan, A., et al. J. Biol. Chem. 281(42):31863-31875(2006) Espejo, F., et al. Biochem. Biophys. Res. Commun. 340(3):860-864(2006) Stehlik, C., et al. Biochem. J. 373 (PT 1), 101-113 (2003) : Pawlowski, K., et al. Trends Biochem. Sci. 26(2):85-87(2001) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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