Human CD263 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD263 |
| Clone | [2B8] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Flow cytometry (FC/FACS), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD263 antibody, clone 2B8 recognizes human CD263, a 60 Kd cell surface protein, which is otherwise known as decoy receptor 1 (DcR1). CD263 is a member of the tumour necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumour cells. The 2B8 antibody does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis. |
| Immunogen | Immunogen: DcR1-Fc chimaeric protein Fusion Partners: Lymph node cells from immunised mice were fused with cells of the P3U1 myeloma cell line Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [tumor necrosis factor receptor superfamily member 10C; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily member 10C; TNF-related apoptosis-inducing ligand receptor 3; antagonist decoy receptor for TRAIL/Apo-2L; cytotoxic TRAIL receptor-3; decoy TRAIL receptor without death domain; decoy receptor 1; lymphocyte inhibitor of TRAIL; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; Antagonist decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor without death domain; Decoy receptor 1; DcR1; Lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL-R3; TRAIL receptor without an intracellular domain; CD_antigen: CD263], [TNFRSF10C; TNFRSF10C; LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR; DCR1; LIT; TRAILR3; TRID; DcR1; TRAIL receptor 3; TRAIL-R3] |
| Gene, Accession # | [CD263], Gene ID: 8794, NCBI: NP_003832.2, UniProt: O14798 |
| Catalog # | MBS214387 |
| Price | $430 |
| Order / More Info | Human CD263 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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