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Antigenic Specificity | EPOR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using EPOR antibody. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen: A synthetic peptide of human EPOR |
Other Names | [erythropoietin receptor; Erythropoietin receptor; erythropoietin receptor; erythropoietin receptor] |
Gene, Accession # | [EPOR], Gene ID: 2057, NCBI: NP_000112.1, UniProt: P19235 |
Catalog # | MBS4150192 |
Price | $385 |
Order / More Info | EPOR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |