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Antigenic Specificity | HRAS (Center), 104-128 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-128 amino acids from the Central region of human HRAS. HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor fo |
Immunogen | n/a |
Other Names | [GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; GTPase HRas; N-terminally processed; HRAS; HRAS1] |
Gene, Accession # | [HRAS], Gene ID: 3265, NCBI: NP_001123914.1, UniProt: P01112 |
Catalog # | MBS9202644 |
Price | $165, $370 |
Order / More Info | HRAS (Center), 104-128 Antibody from MYBIOSOURCE INC. |
Product Specific References | Winter-Vann,A.M., Proc. Natl. Acad. Sci. U.S.A. 100 (11), 6529-6534 (2003) Coats,S.G., Biochemistry 38 (39), 12926-12934 (1999) Sakai,E., Int. J. Cancer 52 (6), 867-872 (1992) |