AIRE - N-terminal region Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-AIRE - N-terminal region antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | AIRE - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription factor playing an essential role to promote self-tolerance in the thymus by regulating the expression of a wide array of self-antigens that have the commonality of being tissue-restricted in their expression pattern in the periphery, called tissue restricted antigens (TRA) (Probable). Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes (By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene express |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse AIRE |
| Other Names | [autoimmune regulator isoform 2; Autoimmune regulator; autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; APECED protein homolog] |
| Gene, Accession # | [AIRE], Gene ID: 11634, NCBI: NP_001258478.1, UniProt: Q9Z0E3 |
| Catalog # | MBS3223591 |
| Price | $335 |
| Order / More Info | AIRE - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies