Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) |
| Clone | [PDPN/1433] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes a muco-protein of 38-43kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
| Immunogen | Immunogen: Recombinant human Podoplanin (PDPN) protein fragment (aa24-126). Cellular Localization: Cell Surface and Cytoplasmic |
| Other Names | [Aggrus; Glycoprotein 36 KD; Glycoprotein 36; gp36; GP38; GP40; HT1A1; hT1alpha1; hT1alpha2; Lung type I cell membrane associated glycoprotein; Lung type I cell membrane associated glycoprotein T1A 2; OTS8; PA2.26; Pdpn; Podoplanin; PSEC0003; PSEC0025; T1-alpha; T1A; TI1A; TIA2], [PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; PICD] |
| Gene, Accession # | [PDPN], Gene ID: 10630, NCBI: NP_001006625.1, UniProt: Q86YL7 |
| Catalog # | MBS439849 |
| Price | $190, $340, $340 |
| Order / More Info | Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Farr, A.G., et al. 1992. Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues. J. Exp. Med. 176: 1477-1482. Schoppmann, S.F., et al. 2001. Lymphatic microvessel density and lymphovascular invasion assessed by anti-podoplanin immunostaining in human breast cancer. Anticancer Res. 21: 2351-2355. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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