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Antigenic Specificity | TGF beta Receptor II |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TGF b Receptor II protein. Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human TGF b Receptor II antibody. |
Other Names | [TGF b Receptor II; GF-beta type II receptor; TGF-betaR2; TGFR-2; TGFR2; kinase TGF-beta-R2] |
Gene, Accession # | [TGF beta], Gene ID: 7048, NCBI: NP_001020018.1, UniProt: P37173 |
Catalog # | MBS9410709 |
Price | $200, $255 |
Order / More Info | TGF beta Receptor II Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |