TGF beta Receptor II Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTGF beta Receptor II
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total TGF b Receptor II protein. Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human TGF b Receptor II antibody.
Other Names[TGF b Receptor II; GF-beta type II receptor; TGF-betaR2; TGFR-2; TGFR2; kinase TGF-beta-R2]
Gene, Accession #[TGF beta], Gene ID: 7048, NCBI: NP_001020018.1, UniProt: P37173
Catalog #MBS9410709
Price$200, $255
Order / More InfoTGF beta Receptor II Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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