Human Endoglin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Endoglin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionEndoglin (ENG, CD105) is an auxiliary receptor for the TGF-beta receptor complex, functioning in related signaling pathways (1,2). Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos (1-4). Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure (5,6). The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial
ImmunogenImmunogen: A fusion protein of human Endoglin
Other Names[Endoglin Rabbit pab], [ENG; CD105; END; FLJ41744; HHT1; ORW; ORW1]
Gene, Accession #Gene ID: 2022, NCBI: NP_000109.1, UniProt: P17813
Catalog #MBS125940
Price$275, $430
Order / More InfoHuman Endoglin Antibody from MYBIOSOURCE INC.
Product Specific References1. Bernabeu, C. et al. (2007) J Cell Biochem 102, 1375-88. 2. Zhu, Y. et al. (2003) Stroke 34, 2483-8. 3. Quintanilla, M. et al. (2003) Oncogene 22, 5976-85. 4. Dallas, N.A. et al. (2008) Clin Cancer Res 14, 1931-7. 5. ten Dijke, P. et al. (2008) Angiogenesis 11, 79-89.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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