EGFR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEGFR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: EGFR (Ab-1092) antibody detects endogenous levels of total EGFR protein. This gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
ImmunogenImmunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1092 (P-E-YP-I-N).
Other Namesn/a
Gene, Accession #[EGFR]
Catalog #MBS417059
Price$405
Order / More InfoEGFR Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBuerger C, et al. (2003) J Biol Chem; 278(39): 37610-21.Wang XQ, (2003) J Biol Chem; 278(49): 48770-8.Saito T, et al. (2004) Endocrinology; 145(9): 4232-43.Pao W, et al. (2004) Proc Natl Acad Sci U S A; 101(36): 13306-11.Mattila E, et al. (2005) Nat Cell Biol; 7(1): 78-85.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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