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Antigenic Specificity | Caspase-12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Inactive caspase-12(CASP12) detection. Tested with WB, IHC-P in Human. Background: Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Csp12L attenuates the inflammatory and innate immune response to endotoxins and in doing so may constitute a risk factor for developing sepsis. The estrogen-mediated inhibition of CSP12L expression is a built-in mechanism that has evolved to protect females from infection by favoring a more robust inflammatory response to pathogens, perhaps notably in childbirth. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12 (71-84aa KIFREHLWNSKKQL). |
Other Names | [Inactive caspase-12; caspase 12(gene/pseudogene); Apoptosis related cysteine protease; CASP 12; CASP-12; casp12; CASP12P1; caspase 12(gene/pseudogene); caspase 12 pseudogene 1; Caspase 12 psuedogene 1; Caspase12; CASPC_HUMAN; Inactive caspase-12; OTTHUMP00000207032; UNQ9415], [CASP12; CASP12; CASP-12; CASP12P1; CASP-12] |
Gene, Accession # | [CASP12], Gene ID: 100506742, NCBI: Q6UXS9.2, UniProt: Q6UXS9 |
Catalog # | MBS176262 |
Price | $315 |
Order / More Info | Caspase-12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |