Caspase-12 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-12
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Inactive caspase-12(CASP12) detection. Tested with WB, IHC-P in Human. Background: Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Csp12L attenuates the inflammatory and innate immune response to endotoxins and in doing so may constitute a risk factor for developing sepsis. The estrogen-mediated inhibition of CSP12L expression is a built-in mechanism that has evolved to protect females from infection by favoring a more robust inflammatory response to pathogens, perhaps notably in childbirth.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12 (71-84aa KIFREHLWNSKKQL).
Other Names[Inactive caspase-12; caspase 12(gene/pseudogene); Apoptosis related cysteine protease; CASP 12; CASP-12; casp12; CASP12P1; caspase 12(gene/pseudogene); caspase 12 pseudogene 1; Caspase 12 psuedogene 1; Caspase12; CASPC_HUMAN; Inactive caspase-12; OTTHUMP00000207032; UNQ9415], [CASP12; CASP12; CASP-12; CASP12P1; CASP-12]
Gene, Accession #[CASP12], Gene ID: 100506742, NCBI: Q6UXS9.2, UniProt: Q6UXS9
Catalog #MBS176262
Price$315
Order / More InfoCaspase-12 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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