HSC70 (HSP73) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HSC70 (HSP73) |
| Clone | [1F2-H5] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a Kappa |
| Format | Protein G purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA), Proximity Ligation Assay (PLA), Protein Binding Assay (PBA), Antibody Microarray (AM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~73kDa. Does not cross react with HSP70. HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated |
| Immunogen | Immunogen: Full length human HSC70 Immunogen Species: Human |
| Other Names | [Mouse Human HSC70 (HSP73) IgG2a Kappa; HSC70 (HSP73), Clone 1F2-H5; HSC54; HSC71; HSC73; HSP71; HSP73; HSPA10; HSPA8; LAP1; NIP71] |
| Gene, Accession # | [HSC70], Gene ID: 3312, NCBI: NP_006588.1, UniProt: P11142 |
| Catalog # | MBS8001902 |
| Price | $245 |
| Order / More Info | HSC70 (HSP73) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Brown C.L. et al. (1993) J.Cell Biol., 120 (5): 1101-1112. 2. Boorstein W.R., Ziegelhoffer T., and Craig E.A. (1993)J. Mol. Evol. 38(1): 1-17. 3. Rothman J. (1989), Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 5. Bork P., Sander C., and Valencia A. (1992) Proc. Nut1Acad. Sci. USA 89: 7290-7294. 6. Brown C.L. et al. (1996) J. Biol. Chem. 271(2): 833-840. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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