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Antigenic Specificity | PTPN6 (Center), 247-277 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PTPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-277 amino acids from the Central region of human PTPN6. PTPN6 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This |
Immunogen | n/a |
Other Names | [Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C] |
Gene, Accession # | [PTPN6], Gene ID: 5777, NCBI: NP_002822.2, UniProt: P29350 |
Catalog # | MBS9203787 |
Price | $165, $370 |
Order / More Info | PTPN6 (Center), 247-277 Antibody from MYBIOSOURCE INC. |
Product Specific References | Korporaal,S.J., Arterioscler. Thromb. Vasc. Biol. 29 (3), 372-379 (2009) Cho,Y.S., Am. J. Respir. Cell Mol. Biol. 39 (4), 412-419 (2008) Christophi,G.P., Lab. Invest. 88 (3), 243-255 (2008) Jones,M.L., J. Biol. Chem. 279 (39), 40475-40483 (2004) |