EZH2 - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | EZH2 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a r |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse EZH2 |
| Other Names | [histone-lysine N-methyltransferase EZH2 isoform 1; Histone-lysine N-methyltransferase EZH2; histone-lysine N-methyltransferase EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit; ENX-1; Enhancer of zeste homolog 2] |
| Gene, Accession # | [EZH2], Gene ID: 14056, NCBI: NP_031997.2, UniProt: Q61188 |
| Catalog # | MBS3223558 |
| Price | $335 |
| Order / More Info | EZH2 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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