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Antigenic Specificity | CD3 zeta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3delta chain, and two CD3epsilon chains. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. CD3 zeta, also known as T-cell receptor T3 zeta chain or CD247, is a 164 amino acids protein with a predicted weight of 18.696 Kda.[1] It plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.[2] |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of human CD3 zeta. |
Other Names | n/a |
Gene, Accession # | [CD3 zeta] |
Catalog # | MBS355180 |
Price | $275 |
Order / More Info | CD3 zeta Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Weissman AM, Hou D, Orloff DG, et al. (December 1988). Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex. Proc. Natl. Acad. Sci. U.S.A. 85 (24): 9709-13. 2. Caplan, S., Zeliger, S., Wang, L., Baniyash, M. Cell-surface-expressed T-cell antigen-receptor epsilon chain is associated with the cytoskeleton. Proc. Nat. Acad. Sci. 92: 4768-4772, 1995. |