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Antigenic Specificity | TLR9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9. |
Other Names | [Toll-like receptor 9] |
Gene, Accession # | [TLR9], Gene ID: 54106, NCBI: AAH32713 |
Catalog # | MBS9414535 |
Price | $320 |
Order / More Info | TLR9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |