CD59 Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD59 Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionDescription: CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene. This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause C
ImmunogenImmunogen: E Coli-derived mouse CD59 recombinant protein (Position: L24-S96). Subcellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.
Other Names[CD59A glycoprotein; MAC-inhibitory protein; MAC-IP; Membrane attack complex inhibition factor; MACIF; Protectin; CD59; Cd59a; Cd59]
Gene, Accession #[CD59], Gene ID: 12509, NCBI: NP_001104530.1, UniProt: O55186
Catalog #MBS1750513
Price$315
Order / More InfoCD59 Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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