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Antigenic Specificity | CD59 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene. This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause C |
Immunogen | Immunogen: E Coli-derived mouse CD59 recombinant protein (Position: L24-S96). Subcellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. |
Other Names | [CD59A glycoprotein; MAC-inhibitory protein; MAC-IP; Membrane attack complex inhibition factor; MACIF; Protectin; CD59; Cd59a; Cd59] |
Gene, Accession # | [CD59], Gene ID: 12509, NCBI: NP_001104530.1, UniProt: O55186 |
Catalog # | MBS1750513 |
Price | $315 |
Order / More Info | CD59 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |