CBX6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCBX6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion. May have a PRC1-independent function in embryonic stem cells.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP 055107.3).
Other Names[chromobox protein homolog 6 isoform 1; Chromobox protein homolog 6; chromobox protein homolog 6; chromobox 6]
Gene, Accession #[CBX6], Gene ID: 23466, NCBI: NP_055107.3, UniProt: O95503
Catalog #MBS8545635
Price$280
Order / More InfoCBX6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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