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Antigenic Specificity | Cathepsin L |
Clone | [CP-L14] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Mouse IgG monoclonal antibody for Cathepsin L, cathepsin L1 (CTSL1) detection. Tested with WB, IHC-F in Human, mouse, rat. No cross reactivity with other proteins. Uniprot ID: P07711 Background: Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required fo |
Immunogen | Immunogen: Procathepsin L isolated from the human lung cancer cell line EPLC 32M1. |
Other Names | [Cathepsin L1; cathepsin L1; CATL; MEP; CTSL; cathepsin L; Major excreted protein], [CTSL; CTSL; MEP; CATL; CTSL1; CTSL1; MEP] |
Gene, Accession # | [CTSL1], Gene ID: 1514, NCBI: P07711.2, UniProt: P07711 |
Catalog # | MBS175048 |
Price | $315 |
Order / More Info | Cathepsin L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |