CD14 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD14 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Coreceptor for bacterial lipopolysaccharide (PubMed: 1698311, PubMed: 23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed: 20133493, PubMed: 23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed: 8612135). Acts as a coreceptor for TLR2: TLR6 heterodimer in response to diacylated lipopeptides and for TLR2: TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed: 16880211). B |
| Immunogen | Immunogen: A synthesized peptide derived from human CD14. Subcellular Localization: Cell membrane; Lipid- anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Secreted forms may arise by cleavage of the GPI anchor. Tissue Specificity: Detected on macrophages (at protein level) (PubMed: 1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. |
| Other Names | [Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14; Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form; CD14], [CD14; CD14] |
| Gene, Accession # | [CD14], Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571 |
| Catalog # | MBS179135 |
| Price | $160, $340, $340 |
| Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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