Edit |   |
---|---|
Antigenic Specificity | CREB2 |
Clone | [80] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic |
Immunogen | Immunogen: Fusion protein of ATF4 |
Other Names | [Activating transcription factor 4; ATF 4; ATF4; ATF4 protein; ATF4; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB-2; CREB2; Cyclic AMP dependent transcription factor ATF 4; Cyclic AMP response element binding protein 2; Cyclic AMP-dependent transcription factor ATF-4; Cyclic AMP-responsive element-binding protein 2; DNA binding protein TAXREB67; DNA-binding protein TAXREB67; Tax Responsive Enhancer Element B67; Tax-responsive enhancer element-binding protein 67; TaxREB67; TXREB] |
Gene, Accession # | [CREB2], Gene ID: 468, NCBI: NP_001666.2, UniProt: P18848 |
Catalog # | MBS2541826 |
Price | $220, $290, $435 |
Order / More Info | CREB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |