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Antigenic Specificity | EPHA4 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EPHA4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 417-451 amino acids from the Central region of human EPHA4. Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ep |
Immunogen | n/a |
Other Names | [Ephrin type-A receptor 4; EPH-like kinase 8; EK8; hEK8; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase receptor SEK; EPHA4; HEK8; SEK; TYRO1] |
Gene, Accession # | [EPHA4], Gene ID: 2043, NCBI: NP_004429.1, UniProt: P54764 |
Catalog # | MBS9203340 |
Price | $165, $370 |
Order / More Info | EPHA4 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Fox G.M.,et al.Oncogene 10:897-905(1995). Richter M.,et al.J. Neurosci. 27:14205-14215(2007). Fu W.Y.,et al.Nat. Neurosci. 10:67-76(2007). Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009). Qin H.,et al.J. Biol. Chem. 283:29473-29484(2008). |