Phospho-SQSTM1 (S403) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-SQSTM1 (S403)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1. This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Immunogenn/a
Other Names[Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA; OSIL]
Gene, Accession #[SQSTM1], Gene ID: 8878, NCBI: NP_001135770.1, UniProt: Q13501
Catalog #MBS9211857
Price$165, $370
Order / More InfoPhospho-SQSTM1 (S403) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesVisconti, M.R., et al. J. Bone Miner. Res. 25(11):2368-2373(2010) Ding, W.X., et al. J. Biol. Chem. 285(36):27879-27890(2010) Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010) Jain, A., et al. J. Biol. Chem. 285(29):22576-22591(2010) Lau, A., et al. Mol. Cell. Biol. 30(13):3275-3285(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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