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Antigenic Specificity | RHOT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist; this antibody will detect all three isoforms. The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4). |
Immunogen | Immunogen: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1. Buffer: RHOT1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Ras homolog family member T1; mitochondrial Rho GTPase 1; ARHT1; MIRO-1; MIRO1; MIRO; ras homolog family member T1], [RHOT1; RHOT1; ARHT1; MIRO1; MIRO-1; ARHT1; MIRO-1; hMiro-1] |
Gene, Accession # | [RHOT1], Gene ID: 55288, NCBI: NP_001028740, UniProt: Q8IXI2 |
Catalog # | MBS153364 |
Price | $375 |
Order / More Info | RHOT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |