RHOT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRHOT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist; this antibody will detect all three isoforms. The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).
ImmunogenImmunogen: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1. Buffer: RHOT1 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Ras homolog family member T1; mitochondrial Rho GTPase 1; ARHT1; MIRO-1; MIRO1; MIRO; ras homolog family member T1], [RHOT1; RHOT1; ARHT1; MIRO1; MIRO-1; ARHT1; MIRO-1; hMiro-1]
Gene, Accession #[RHOT1], Gene ID: 55288, NCBI: NP_001028740, UniProt: Q8IXI2
Catalog #MBS153364
Price$375
Order / More InfoRHOT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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