FOXP3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FOXP3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, cat, human, monkey, mouse, rat. predicted: porcine, cynomolgus monkey, rhesus monkey, deer |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.7 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/ Paraffin, Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Forkhead box protein 3 Antibody. Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. Can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases. The suppressive activity of Treg involves the coordinate activation of many genes, including CTLA4 and TNFRSF18 by FOXP3 along with repression of genes encoding cytokines such as |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 229-250 of Mouse Forkhead Box Protein 3 (winged helix transcription factor 3 protein). The peptide was post synthetically modified to achieve desired antigenicity before coupling to a carrier protein. Sequence: AQCLLQREVVQSLEQQLELEKE. Immunoglobulin: IgG. Expression: Down-regulated in regulatory T-cells (Treg) during inflammation. |
| Other Names | [AIID; DIETER; Forkhead box P3; FOXP3delta7; Immune dysregulation polyendocrinopathy enteropathy X linked; IPEX; JM2; MGC141961; MGC141963; PIDX; SCURFIN; XPID], [C11orf1; C11orf1] |
| Gene, Accession # | [FOXP3], Gene ID: 64776, NCBI: Q9H5F2.1, UniProt: Q9H5F2 |
| Catalog # | MBS540024 |
| Price | $390 |
| Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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