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Antigenic Specificity | Mouse CD150 |
Clone | [TC15-12F12.2] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, lambda |
Format | phycoerythrin (PE) conjugate |
Size | 50 tests, 100 tests, 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-gamma production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal |
Immunogen | n/a |
Other Names | [Slam; Slamf1; CD 150; Signaling lymphocytic activation molecule] |
Gene, Accession # | [CD150], Gene ID: 27218, NCBI: NP_038758.2, UniProt: Q9QUM4 |
Catalog # | MBS2559246 |
Price | $70, $85, $135 |
Order / More Info | Mouse CD150 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |