Human m7GpppN-mRNA hydrolase Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman m7GpppN-mRNA hydrolase
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionDecapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.
ImmunogenImmunogen: Recombinant human m7GpppN-mRNA hydrolase (1-385aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26085 / sc-26084 / sc-133650
Other Names[Nucleoside diphosphate-linked moiety X motif 20; mRNA-decapping enzyme 2; NUDT20; DCP2], [DCP2; DCP2; NUDT20; NUDT20; Nudix motif 20; hDpc]
Gene, Accession #Gene ID: 167227, NCBI: NP_001229306.1, UniProt: Q8IU60
Catalog #MBS1492175
Price$160, $235
Order / More InfoHuman m7GpppN-mRNA hydrolase Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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