Edit |   |
---|---|
Antigenic Specificity | Human m7GpppN-mRNA hydrolase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. |
Immunogen | Immunogen: Recombinant human m7GpppN-mRNA hydrolase (1-385aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26085 / sc-26084 / sc-133650 |
Other Names | [Nucleoside diphosphate-linked moiety X motif 20; mRNA-decapping enzyme 2; NUDT20; DCP2], [DCP2; DCP2; NUDT20; NUDT20; Nudix motif 20; hDpc] |
Gene, Accession # | Gene ID: 167227, NCBI: NP_001229306.1, UniProt: Q8IU60 |
Catalog # | MBS1492175 |
Price | $160, $235 |
Order / More Info | Human m7GpppN-mRNA hydrolase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |