Cathepsin D Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cathepsin D antibody, protein, ELISA kits.
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| Antigenic Specificity | Cathepsin D |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Cathepsin D. Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins (1). It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) (2). Cathepsin D may also be secreted into the cytosol during apoptosis and contribute to cleavage of substrates implicated in the apoptotic pathway (3). Numerous studies have suggested that cathepsin D plays a role in neuronal degradation and malignant transformation, particularily in breast cancer (4-9). |
| Immunogen | Immunogen: Fusion protein of human Cathepsin D |
| Other Names | [CTSD; Cathepsin D; Cathepsin D; CTSD; CLN10; CPSD; MGC2311], [CTSD; CTSD; CPSD; CLN10; CPSD] |
| Gene, Accession # | Gene ID: 1509, NCBI: NP_001900.1, UniProt: P07339 |
| Catalog # | MBS125225 |
| Price | $275, $430 |
| Order / More Info | Cathepsin D Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Faust, P.L. et al. (1985) Proc. Natl. Acad. Sci. USA 82, 4910-4914. 2. Erickson, A.H. et al. (1981) J. Biol.Chem. 256, 11224-11231. 3. Liaudet-Coopman, E. et al. (2006) Cancer Lett. 237, 167-179. 4. Berchem, G. et al. (2002) Oncogene 21, 5951-5955. 5. Nomura, T. and Katunuma, N. (2005) J. Med. Invest. 52, 1-9. 6. Garcia, M. et al. (1996) Stem Cells 14, 642-560. 7. Nogami, M. et al. (2000) Histochem. J. 32, 505-508. 8. Nakanishi, H. (2003) Ageing Res. Rev. 2, 367-381. 9. Callahan, L.M. et al. Neurobiol. Aging 19, S99-105. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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