CTNND1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTNND1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionCatenin delta-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function (1). Catenin delta-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion (2). Catenin delta-1 has both positive and negative effects on cadherin-mediated adhesion (3). Actin dynamics are also regulated by catenin delta-1, which modulates RhoA, Rac, and cdc42 proteins (1). Analogous to beta-catenin, catenin delta-1 translocates to the nucleus
ImmunogenImmunogen: Recombinant protein of human CTNND1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[CAS; CTNND; KIAA0384; P120CAS; P120CTN; p120]
Gene, Accession #[CTNND1], Gene ID: 1500, NCBI: NP_001078927.1, UniProt: O60716
Catalog #MBS8503687
Price$310
Order / More InfoCTNND1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Reynolds, A.B. and Roczniak-Ferguson, A. (2004) Oncogene 23, 7947-7956. 2. Davis, M. A. et al. (2003) J. Cell Biol. 163, 525-534. 3. Thoreson, M.A. and Reynolds, A.B. (2002) Differentiation 70, 583-589. 4. Anastasiadis, P.Z. and Reynolds, A.B. (2000) J. Cell Sci. 113, 1319-1334. 5. Rush, J. et al. (2005) Nat. Biotechnol. 23, 94-101.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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