Mouse GITR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse GITR |
| Clone | [YGIR765.4.16] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.25 mg |
| Concentration | Antibody concentration: 1.0 mg/ml |
| Applications | Functional Assay (FA), In-Vivo Depletion (IV), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: GITR (Mouse GITR). GITR antibody (clone YGITR 765.4.16) detects mouse GITR (also called TNFRSF18), a 228 aa cysteine-rich protein with a molecular weight of approximately 25 kDa. GITR is a type I transmembrane protein belonging to the tumor necrosis factor/nerve growth factor receptor (TNF/NGFR) family. The mouse GITR gene was localized to murine chromosome 4 (E region) where other TNF/NGFR members localize, including mouse 4- 1BB and OX40. Mouse GITR is expressed at low levels on unstimulated T cells, B cells and macrophages, and increases upon stimulation. GITR promotes the activation, survival and cytokine production of T cells, and can induce the activation of NF-kB and three subfamilies of MAP kinases; ERKs, JNK's and p38. |
| Immunogen | Immunogen: Mouse GITR transfectant. Donor: DA rat spleen. Fusion Partner: Y3/Ag 1.2.3 |
| Other Names | n/a |
| Gene, Accession # | [GITR], NCBI: ACT80311.1 |
| Catalog # | MBS520311 |
| Price | $350 |
| Order / More Info | Mouse GITR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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