Edit |   |
---|---|
Antigenic Specificity | ZFP219 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of ZFP219 are known to exist; this antibody will recognize both. ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulati |
Immunogen | Immunogen: ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219. Buffer: ZFP219 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ZFP219; ZFP219; Zinc finger protein 219; zinc finger protein 219], [ZNF219; ZNF219; ZFP219] |
Gene, Accession # | [ZNF219], Gene ID: 51222, NCBI: NP_001095142, UniProt: Q9P2Y4 |
Catalog # | MBS150420 |
Price | $375 |
Order / More Info | ZFP219 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |