HSP90 alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HSP90 alpha |
| Clone | [Hyb-K41009] |
| Host Species | Mouse |
| Reactive Species | human; mouse; rat |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | n/a |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects 90kDa. This is an alpha-specific product. HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer (2). From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (3-6). Furthermore, HSP90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeas |
| Immunogen | Immunogen: Recombinant human HSP90alpha; Specificity mapped to amino acids 604-731. Immunogen Species: Human. Cellular Localization: Cytoplasm; Melanosome. Conjugate: Unconjugated. Storage Buffer: PBS pH7.2, 50% glycerol, 0.09% sodium azide |
| Other Names | [Mouse Human HSP90 alpha IgG2a; HSP90 alpha; HSP86; HSP89A; HSP90A; HSP90AA1; HSP90Alpha; HSPC1; HSPCA; HSPCAL3], [HSP90AA1; HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; Hsp103; HSPCAL1; HSPCAL4; HEL-S-65p; HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2] |
| Gene, Accession # | [HSP90 alpha], Gene ID: 3320, NCBI: NP_001017963.2, UniProt: P07900 |
| Catalog # | MBS808267 |
| Price | please inquire |
| Order / More Info | HSP90 alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemoto, T. et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem. 278: 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem. 59: 157-186. 5. Neckers L, et al. (2002) Trends Mol Med. 8: S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med. 228: 111-133. 7. Pratt W, Toft D. (1997) Endocr Rev. 18: 306-360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med. 217: 420-434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA. 91: 8324-8328. 10. Nemoto, T. (1997) Biochem and Mol. Bio Intl. 42 (5): 881-889. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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