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Antigenic Specificity | Vitronectin Receptor/CD51/CD61 |
Clone | [23C6] |
Host Species | Mouse |
Reactive Species | human, chickendoes not react with bovine or porcine or rabbit. |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin Receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing r |
Immunogen | Immunogen: Osteoclasts from osteoclastomas |
Other Names | [CD51; DKFZp686A08142; integrin alpha V beta 3; Integrin alpha-5 Integrin alpha-V light chain; integrin alphaVbeta3; integrin; alpha V (vitronectin receptor; alpha polypeptide; antigen CD51); ITGAV; Msk8; VNRA; VTNR] |
Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: NP_001138471.1, UniProt: P06756 |
Catalog # | MBS4381466 |
Price | $190, $340, $340 |
Order / More Info | Vitronectin Receptor/CD51/CD61 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kotake, S et al. Cell Biol Int. 2013 Jan;37(1):65-77. |