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Antigenic Specificity | H2AFZ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFZ (NP 002097.1). |
Other Names | [H2AZ; H2A.z; H2A/z; H2A.Z-1] |
Gene, Accession # | [H2AFZ], Gene ID: 3015, NCBI: NP_002097.1, UniProt: P0C0S5 |
Catalog # | MBS8546233 |
Price | $280 |
Order / More Info | H2AFZ Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |