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Antigenic Specificity | IGF2BP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. |
Immunogen | Immunogen: Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA) |
Other Names | [Insulin-like growth factor 2 mRNA-binding protein 3IGF2 mRNA-binding protein 3IMP-3; IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3; IGF2BP3; IMP3; KOC1; VICKZ3] |
Gene, Accession # | [IGF2BP3], Gene ID: 10643, NCBI: NP_006538.2, UniProt: O00425 |
Catalog # | MBS7048444 |
Price | $160, $235 |
Order / More Info | IGF2BP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |